Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM50428343'
TargetBeta-secretase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50428343(CHEMBL2331708)
Affinity DataIC50:  5nMAssay Description:Inhibition of BACE1 in human HEK293 cells transfected with human wild type APP695 assessed as decrease in amyloid beta 40 level after 18 to 20 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50428343(CHEMBL2331708)
Affinity DataIC50:  5nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing APP695 assessed as inhibition of amyloid beta (1 to 40) production after 18 to 20 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed