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Found
1
Enz. Inhib. hit(s) with Target = 'Beta-secretase 1 [1-458]' and Ligand = 'BDBM195115'
Target
Beta-secretase 1 [1-458]
(Homo sapiens (Human))
Vitae Pharmaceuticals
US Patent
Ligand
BDBM195115
(US9212153, 174,Ex. 136)
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Affinity Data
IC50: 23.5nM
pH: 4.4
Assay Description:
For each compound being tested, the BACE activity was monitored in a fluorescence quenching assay (FRET) using the ectodomain of BACE (aa 1-454) fuse...
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Target Info
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Ligand Info
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