Compile Data Set for Download or QSAR
maximum 50k data
Found 1 Enz. Inhib. hit(s) with Target = 'Beta-secretase 2' and Ligand = 'BDBM190749'
TargetBeta-secretase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM190749(US9181236, 47a)
Affinity DataKi: <50nM ΔG°: <-42.4kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISE...More data for this Ligand-Target Pair
In DepthDetails US Patent