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Found 3 Enz. Inhib. hit(s) with Target = 'Bifunctional epoxide hydrolase 2' and Ligand = 'BDBM50295543'
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50295543(CHEMBL564757 | N-(2-phenylcyclopropyl)-4-(3-(pyrid...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50295543(CHEMBL564757 | N-(2-phenylcyclopropyl)-4-(3-(pyrid...)
Affinity DataIC50:  10nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50295543(CHEMBL564757 | N-(2-phenylcyclopropyl)-4-(3-(pyrid...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human sEH in HEK293 cells assessed as conversion of 14,15-epoxyeicosatrienoic acid to 14,15-dihydroepoxyeicosatrienoic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed