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Found 7 Enz. Inhib. hit(s) with Target = 'Bifunctional purine biosynthesis protein ATIC' and Ligand = 'BDBM50005520'
TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005520((S)-2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimid...)
Affinity DataIC50:  700nMAssay Description:Hexaglutamyl homologue inhibition activity against the AICAR formyltransferase was determined against L cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005520((S)-2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimid...)
Affinity DataIC50:  700nMAssay Description:Inhibition activity against Glycinamide ribonucleotide transformylase(GAR-TFase) against hog liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005520((S)-2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimid...)
Affinity DataIC50:  1.90E+3nMAssay Description:Triglutamyl homologue inhibition activity against AICAR formyltransferase was determined against L cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005520((S)-2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimid...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition activity against AICAR formyltransferase determined against MOLT-4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005520((S)-2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimid...)
Affinity DataIC50:  9.40E+4nMAssay Description:In vitro inhibitory activity of the compound against MOLT-4 T-cell leukemia cell AICAR transformylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005520((S)-2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimid...)
Affinity DataIC50:  9.40E+4nMAssay Description:Inhibition activity against AICAR formyltransferase determined against MOLT-4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005520((S)-2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimid...)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibition activity against AICAR formyltransferase determined against MOLT-4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed