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Found 2 Enz. Inhib. hit(s) with Target = 'Bile acid receptor' and Ligand = 'BDBM50527043'
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527043(CHEMBL4527188)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527043(CHEMBL4527188)
Affinity DataEC50:  1.10E+4nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed