Found 2 Enz. Inhib. hit(s) with Target = 'Calcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1' and Ligand = 'BDBM50184072'
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department Of Medicinal Chemistry Merck
Curated by ChEMBL
Department Of Medicinal Chemistry Merck
Curated by ChEMBL
Affinity DataKi: 61nMAssay Description:Displacement of [125I]CGRP from human cloned CLR/RAMP1 receptor expressed in E10 cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department Of Medicinal Chemistry Merck
Curated by ChEMBL
Department Of Medicinal Chemistry Merck
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Antagonist activity at human cloned CLR/RAMP1 receptor expressed in E10 cells measured as inhibition of CGRP-mediated cAMP productionMore data for this Ligand-Target Pair