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Found 2 Enz. Inhib. hit(s) with Target = 'Calcium/calmodulin dependent protein kinase with a kinas domain and 4 calmodulin-like EF hands' and Ligand = 'BDBM50345732'
TargetCalcium/calmodulin dependent protein kinase with a kinas domain and 4 calmodulin-like EF hands(Cryptosporidium parvum (strain Iowa II))
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50345732(1-isopropyl-3-(4-methoxyphenyl)-1H-pyrazolo[3,4-d]...)
Affinity DataIC50:  410nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCalcium/calmodulin dependent protein kinase with a kinas domain and 4 calmodulin-like EF hands(Cryptosporidium parvum (strain Iowa II))
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50345732(1-isopropyl-3-(4-methoxyphenyl)-1H-pyrazolo[3,4-d]...)
Affinity DataIC50:  410nMAssay Description:Kinase phosphorylation reactions were performed in a buffered medium containing 20 mM HEPES pH 7.5 (KOH), 0.1% BSA, 10 mM MgCl2, 1 mM EGTA (pH 7.2), ...More data for this Ligand-Target Pair
In DepthDetails US Patent