Found 5 Enz. Inhib. hit(s) with Target = 'Cannabinoid receptor 1' and Ligand = 'BDBM85804' TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Virginia Commonwealth University
Curated by PDSP Ki Database
Virginia Commonwealth University
Curated by PDSP Ki Database
Affinity DataKi: 12.9nM ΔG°: -45.0kJ/moleT: 2°CAssay Description:Competition receptor binding was performed as previously described [Shoemaker et al., J. Pharmacol. Exp. Ther., 314:868-75]. Briefly, 50 μg of mou...More data for this Ligand-Target Pair
Affinity DataKi: 12.9nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Agonist activity at CB1 receptor in mouse Neuro2a cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 mins by liq...More data for this Ligand-Target Pair
Affinity DataEC50: 277nMT: 2°CAssay Description:[35S]GTPγS binding was performed as previously described [Brents et al., PLoS One, 6:e21917]. Briefly, 25 μg of mouse brain homogenates were...More data for this Ligand-Target Pair
