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Found 2 Enz. Inhib. hit(s) with Target = 'Chitotriosidase-1' and Ligand = 'BDBM388676'
TargetChitotriosidase-1(Homo sapiens (Human))
Oncoarendi Therapeutics

US Patent
LigandPNGBDBM388676(1-((2S,5S)-4-(1-(5-amino-4H-1,2,4-triazol-3-yl)pip...)
Affinity DataIC50: <300nMAssay Description:An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetChitotriosidase-1(Homo sapiens (Human))
Oncoarendi Therapeutics

US Patent
LigandPNGBDBM388676(1-((2S,5S)-4-(1-(5-amino-4H-1,2,4-triazol-3-yl)pip...)
Affinity DataIC50: >1.00E+3nMAssay Description:An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent