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Found
1
Enz. Inhib. hit(s) with Target = 'Coagulation factor XI' and Ligand = 'BDBM652618'
Target
Coagulation factor XI
(Homo sapiens (Human))
Kalvista Pharmaceuticals
US Patent
Ligand
BDBM652618
(N6-(2-fluoro-4-((((4R*,5R*)-2-methyl-2-azabicyclo[...)
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Affinity Data
IC50: 2nM
Assay Description:
In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...
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Target Info
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Reactome pathway
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antibodypedia
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Ligand Info
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PC sid
In Depth
Details
US Patent
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