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Found 1 Enz. Inhib. hit(s) with Target = 'Coagulation factor XII' and Ligand = 'BDBM22859'
TargetCoagulation factor XII(Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM22859(1,2-Dione-Based Compound, 16 | 1,2-dihydroaceanthr...)
Affinity DataKi:  7.70nM ΔG°:  -46.3kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed