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Found 2 Enz. Inhib. hit(s) with Target = 'Coiled-coil domain-containing protein 6/Proto-oncogene tyrosine-protein kinase receptor Ret' and Ligand = 'BDBM625348'
TargetCoiled-coil domain-containing protein 6/Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Jiangsu Chia Tai Fenghai Pharmaceutical

US Patent
LigandPNGBDBM625348(US20230322769, Compound 57 | US20230322769, Compou...)
Affinity DataIC50:  1.13nMAssay Description:The activity assay method for the above kinases was established by homogeneous time-resolved fluorescence (HTRF), and the inhibitory activity of the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoiled-coil domain-containing protein 6/Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Jiangsu Chia Tai Fenghai Pharmaceutical

US Patent
LigandPNGBDBM625348(US20230322769, Compound 57 | US20230322769, Compou...)
Affinity DataIC50:  4.44nMAssay Description:The activity assay method for the above kinases was established by homogeneous time-resolved fluorescence (HTRF), and the inhibitory activity of the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent