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Found 2 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 4' and Ligand = 'BDBM50330268'
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50330268(4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-N-(5-(pip...)
Affinity DataIC50:  134nMAssay Description:Inhibition of CDK4 in human Jeko1 cells assessed as phosphorylated pRb at Ser780 level after 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50330268(4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-N-(5-(pip...)
Affinity DataIC50:  383nMAssay Description:Inhibition of CDK4 in human Jeko1 cells assessed as phosphorylated pRb at Ser780 level after 2 hrs by ELISA relative to total pRb levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed