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Found 1 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 2D6' and Ligand = 'BDBM50029668'
TargetCytochrome P450 2D6(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate preincubated for 10 mins in presence of NADPH generating system fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed