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Found 2 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 3A4' and Ligand = 'BDBM50218812'
TargetCytochrome P450 3A4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50218812((3R,4R)-3,4-bis(1,3-benzodioxol-5-ylmethyl)dihydro...)
Affinity DataKi:  373nMAssay Description:Mechanism based inhibition of human cytochrome P450 3A4 measured by (14C)formaldehyde production from (N-methyl-14C)-erythromycinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50218812((3R,4R)-3,4-bis(1,3-benzodioxol-5-ylmethyl)dihydro...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human liver microsome CYP3A4 in assessed as [14C]formaldehyde formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed