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Found 4 Enz. Inhib. hit(s) with Target = 'Cytosolic phospholipase A2' and Ligand = 'BDBM50185349'
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of MüNster

Curated by ChEMBL
LigandPNGBDBM50185349(3-formyl-1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-ind...)
Affinity DataIC50:  9.70nMAssay Description:Inhibition of cPLA2-alpha activity assessed by TPA-induced arachidonic acid release in human plateletMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of MüNster

Curated by ChEMBL
LigandPNGBDBM50185349(3-formyl-1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-ind...)
Affinity DataIC50:  16nMAssay Description:Inhibition of cPLA2 from human platelets by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of MüNster

Curated by ChEMBL
LigandPNGBDBM50185349(3-formyl-1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-ind...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human isolated cPLA2alpha by vescicle assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of MüNster

Curated by ChEMBL
LigandPNGBDBM50185349(3-formyl-1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-ind...)
Affinity DataIC50:  380nMAssay Description:Inhibition of cPLA2alpha activity assessed by A23187-induced arachidonic acid release in human plateletMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed