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Found 22 Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50020680'
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)
Affinity DataKi:  7.20nMAssay Description:Binding affinity towards Dopamine receptor D2 by displacement of [3H]-U-86,170.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)
Affinity DataKi:  676nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)
Affinity DataKi:  676nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)
Affinity DataKi:  692nMAssay Description:Displacement of [3H]spiperone form human cloned dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)
Affinity DataKi:  933nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)
Affinity DataKi:  933nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)
Affinity DataKi:  1.15E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)
Affinity DataKi:  2.67E+3nMAssay Description:Displacement of [3H]spiperone from rat D2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)
Affinity DataIC50:  1.80E+3nMAssay Description:Displacement of [3H]nemonapride from Rattus norvegicus (rat) wild type dopamine D2 receptor transfected in african green monkey COS7 cells after 1 hr...More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)
Affinity DataIC50:  6.81E+3nMAssay Description:Displacement of [3H]-spiroperidol from homogenized bovine pituitary Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)
Affinity DataEC50:  304nMAssay Description:Agonist activity at human dopamine D2L receptor expressed in CHO cells assessed as stimulation of [35S]GTPgamma bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)
Affinity DataEC50:  304nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)
Affinity DataEC50:  304nMAssay Description:Agonist activity at human dopamine D2L receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)
Affinity DataEC50:  304nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)
Affinity DataEC50:  302nMAssay Description:Agonist activity at human dopamine D2L receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)
Affinity DataEC50:  30nMAssay Description:Partial agonist activity at human D2SR expressed in HEK293T cells co-expressing (EA)beta-arrestin2 and GRK2 assessed as induction of beta-arrestin2 r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)
Affinity DataEC50:  89nMAssay Description:Partial agonist activity at human D2SR expressed in HEK293T cells co-expressing (EA)beta-arrestin2 assessed as induction of beta-arrestin2 recruitmen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)
Affinity DataEC50:  89nMAssay Description:Agonist activity at human D2SR expressed in HEK293 cells incubated for 5 hrs by beta-Arrestin 2 recruitment assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)
Affinity DataEC50:  330nMAssay Description:Displacement of [3H]spiperone from human D4R expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)
Affinity DataEC50:  76nMAssay Description:Agonist activity at Rattus norvegicus (rat) dopamine D2 receptor transfected in african green monkey COS7 cells assessed as inhibition of forskolin-s...More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)
Affinity DataEC50:  83nMAssay Description:Agonist activity at human recombinant dopamine D2 receptor expressed in rat pituitary cells assessed as inhibition of forskolin-stimulated cAMP accum...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)
Affinity DataEC50:  330nMAssay Description:Agonist activity at human D2S receptor expressed in HEK293T cell membranes coexpressing Galphao1 assessed as induction of nucleotide exchange preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank