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Found 2 Enz. Inhib. hit(s) with Target = 'DNA ligase A' and Ligand = 'BDBM22986'
TargetDNA ligase A(Mycobacterium tuberculosis)
Central Drug Research Institute

LigandPNGBDBM22986(18-[6-(piperidin-1-yl)hexyl]-8-thia-18-azatetracyc...)
Affinity DataIC50:  1.35E+4nMAssay Description:All assays have been carried out using procedures previously described by our group (Srivastava et al., 2005a; 2005b; 2007)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetDNA ligase A(Mycobacterium tuberculosis)
Central Drug Research Institute

LigandPNGBDBM22986(18-[6-(piperidin-1-yl)hexyl]-8-thia-18-azatetracyc...)
Affinity DataIC50:  1.35E+4nMpH: 8.0 T: 2°CAssay Description:The assay was performed using a 40-bp double-stranded DNA substrate carrying a single-strand nick between bases 22 and 23. The reaction products were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed