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Found 2 Enz. Inhib. hit(s) with Target = 'Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial' and Ligand = 'BDBM50395031'
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50395031(CHEMBL2163854)
Affinity DataIC50:  29nMAssay Description:Inhibition of human dUTPase assessed as reduction in [5-3H]dUMP production incubated for 15 mins by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50395031(CHEMBL2163854)
Affinity DataEC50:  50nMAssay Description:Inhibition of dUTPase in human HeLa S3 cells assessed as potentiation of 1 uM FdUrd-induced decrease in cell density incubated for 48 hrs by crystal ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed