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Found 2 Enz. Inhib. hit(s) with Target = 'Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial' and Ligand = 'BDBM5423'
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM5423(CHEMBL2057594 | US8530490, 135)
Affinity DataIC50:  1.12E+3nMAssay Description:The inhibitory activity of the compound against human dUTPase was determined by measuring the production of [5-3H]deoxyuridine monophosphate from [5-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM5423(CHEMBL2057594 | US8530490, 135)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human dUTPase assessed as production of [5-3H]dUMP from [5-3H]dUTP after 15 mins measured by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed