Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50128534'
TargetDihydrofolate reductase(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128534(5-(4,11-Dimethyl-1,2,4,11-tetrahydro-pyrido[4,3-a]...)
Affinity DataIC50:  4nMAssay Description:Antibacterial activity of TMP-susceptible Dihydrofolate reductase against Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128534(5-(4,11-Dimethyl-1,2,4,11-tetrahydro-pyrido[4,3-a]...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity of TMP-susceptible Dihydrofolate reductase against Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128534(5-(4,11-Dimethyl-1,2,4,11-tetrahydro-pyrido[4,3-a]...)
Affinity DataIC50:  85nMAssay Description:Antibacterial activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus pneumoniae 1/1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Staphylococcus aureus (strain MW2))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128534(5-(4,11-Dimethyl-1,2,4,11-tetrahydro-pyrido[4,3-a]...)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibitory activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus aureus 157/4696More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed