Found 24 Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 1' and Ligand = 'BDBM50195235' TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of DPP1 in human U937 cells using Gly-Phe-AFC as substrate preincubated for 60 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant DPP1 using Gly-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorometric assayMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 4.47nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 4.47nMAssay Description:Examples 1-35: The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 4.47nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 4.47nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 4.47nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 4.47nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 4.47nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of amino methyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whi...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 4.47nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of Cathepsin C in human THP-1 cells using H-Gly-Phe-AFC as substrate pretreated for 1 hr followed by substrate addition and incubated for ...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human Cathepsin C in human THP-1 cells using H-Gly-Phe-AFC as substrate pretreated for 60 mins followed by substrate addition incubated...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human Cathepsin C in human U-937 cells using H-Gly-Phe-AFC as substrate pretreated for 60 mins followed by substrate addition incubated...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of Cathepsin C in human U-937 cells using H-Gly-Phe-AFC as substrate pretreated for 1 hr followed by substrate addition and incubated for ...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Canis lupus familiaris)
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of dog DPP1 using Gly-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorometric assayMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant Cathepsin C using H-Gly-Arg-AMC as substrate pretreated for 30 mins followed by substrate addition incubated for 60 m...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant Cathepsin C using H-Gly-Arg-AMC as substrate pretreated for 30 mins followed by substrate addition and incubated for ...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Rattus norvegicus)
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of rat DPP1 using Gly-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorometric assayMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Mus musculus)
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of mouse DPP1 using Gly-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorometric assayMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of DPP1 in human primary bone marrow-derived CD34+ neutrophil progenitor cells assessed as inactivation of neutrophil elastase using metho...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 115nMAssay Description:Inhibition of DPP1 in human primary bone marrow-derived CD34+ neutrophil progenitor cells assessed as inactivation of cathepsin G using N-succinyl-Al...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 141nMAssay Description:Inhibition of DPP1 in human primary bone marrow-derived CD34+ neutrophil progenitor cellsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 209nMAssay Description:Inhibition of DPP1 in human primary bone marrow-derived CD34+ neutrophil progenitor cells assessed as inactivation of proteinase 3 using aminobenzoyl...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataKd: 2.5nMAssay Description:Reversible inhibition of human recombinant DPP1 by surface plasmon resonance direct binding assayMore data for this Ligand-Target Pair
