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Found
1
Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 4' and Ligand = 'BDBM140271'
Target
Dipeptidyl peptidase 4
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM140271
(US8907086, Example 7)
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Affinity Data
IC50: 14nM
pH: 7.5 T: 2°C
Assay Description:
DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...
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Target Info
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Ligand Info
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US Patent
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