Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 17' and Ligand = 'BDBM175083'
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM175083(US9115102, Ex14 | US9115102, Ex24)
Affinity DataIC50:  35nMpH: 7.4Assay Description:The TACE enzyme is an internal production (carried out according to the publication protein Eng Des Sel, 2006, 19, 155-161) and is added so as to hav...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM175083(US9115102, Ex14 | US9115102, Ex24)
Affinity DataIC50:  35nMAssay Description:The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM175083(US9115102, Ex14 | US9115102, Ex24)
Affinity DataIC50:  88nMpH: 7.4Assay Description:The TACE enzyme is an internal production (carried out according to the publication protein Eng Des Sel, 2006, 19, 155-161) and is added so as to hav...More data for this Ligand-Target Pair
In DepthDetails US Patent