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Found 5 Enz. Inhib. hit(s) with Target = 'Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B' and Ligand = 'BDBM279101'
LigandPNGBDBM279101(5-(2-ethoxy-3-pyridyl)-3-methyl-N-[(1-methylimidaz...)
Affinity DataIC50:  0.0450nMpH: 7.6 T: 2°CAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM279101(5-(2-ethoxy-3-pyridyl)-3-methyl-N-[(1-methylimidaz...)
Affinity DataIC50:  0.0450nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM279101(5-(2-ethoxy-3-pyridyl)-3-methyl-N-[(1-methylimidaz...)
Affinity DataIC50:  0.0450nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM279101(5-(2-ethoxy-3-pyridyl)-3-methyl-N-[(1-methylimidaz...)
Affinity DataIC50:  0.0450nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM279101(5-(2-ethoxy-3-pyridyl)-3-methyl-N-[(1-methylimidaz...)
Affinity DataIC50:  0.0450nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent