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Found 2 Enz. Inhib. hit(s) with Target = 'Dual specificity protein kinase CLK1' and Ligand = 'BDBM50073765'
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50073765(CHEMBL367625 | N*2*-((1R,2S)-2-Amino-cyclohexyl)-N...)
Affinity DataIC50:  148nMAssay Description:Inhibition of human CLK1 using substrate ERMRPRKRQGSVRRRV in presence of [gamma-33P]ATP after 40 mins by scintillation counter methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50073765(CHEMBL367625 | N*2*-((1R,2S)-2-Amino-cyclohexyl)-N...)
Affinity DataEC50:  4.20E+3nMAssay Description:Inhibition of CLK mediated SF3B1 activation in human SK-MEL-2 cells assessed as MDM2-pre mRNA exon skipping after 4 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed