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Found 2 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase XIAP' and Ligand = 'BDBM50450046'
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50450046(CHEMBL4173974)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of full length FLAG-tagged XIAP (unknown origin) interaction with full length untagged caspase-9 expressed in HEK293 cells after 2 hrs by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50450046(CHEMBL4173974)
Affinity DataIC50: <40nMAssay Description:Inhibition of XIAP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed