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Found 1 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase XIAP [124-240]' and Ligand = 'BDBM412162'
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM412162(N-((S)-3-((2,6- difluorophenyl)carbamoyl)- 2-((S)-...)
Affinity DataIC50:  7nMAssay Description:For the Bir2 assay, 3.5 nanomolar of 6× Histidine-tagged BIR2 domain (6× Histidine disclosed as SEQ ID NO: 25), corresponding to amino acids 124-240 ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent