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Found 6 Enz. Inhib. hit(s) with Target = 'Egl nine homolog 1' and Ligand = 'BDBM102348'
TargetEgl nine homolog 1(Homo sapiens (Human))
Aerpio Therapeutics

US Patent
LigandPNGBDBM102348(US10562854, No. A41 | US8536181, A41 | US9278930, ...)
Affinity DataIC50:  1.40E+4nMAssay Description:EGLN enzyme activity assay is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALDI-TOF MS.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Aerpio Therapeutics

US Patent
LigandPNGBDBM102348(US10562854, No. A41 | US8536181, A41 | US9278930, ...)
Affinity DataIC50:  1.40E+4nMpH: 7.5Assay Description:The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALDI-T...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Aerpio Therapeutics

US Patent
LigandPNGBDBM102348(US10562854, No. A41 | US8536181, A41 | US9278930, ...)
Affinity DataIC50:  1.40E+4nMAssay Description:The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALDI-T...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Aerpio Therapeutics

US Patent
LigandPNGBDBM102348(US10562854, No. A41 | US8536181, A41 | US9278930, ...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human recombinant EGLN-1 using DLDLEALAPYIPADDDFQL as substrate after 20 mins by mass spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Aerpio Therapeutics

US Patent
LigandPNGBDBM102348(US10562854, No. A41 | US8536181, A41 | US9278930, ...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of HIF-PHD2 (unknown origin) expressed in insect Hi5 cells using peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Aerpio Therapeutics

US Patent
LigandPNGBDBM102348(US10562854, No. A41 | US8536181, A41 | US9278930, ...)
Affinity DataEC50:  1.70E+4nMAssay Description:Inhibition of PHD2 in HEK293 cells assessed as VEGF release by immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed