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Found 3 Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM50506505'
TargetEndothelial lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506505(CHEMBL4460376)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of EL in human HT1080 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506505(CHEMBL4460376)
Affinity DataIC50:  200nMAssay Description:Inhibition of EL in human HT1080 cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of human serum by LC/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50506505(CHEMBL4460376)
Affinity DataIC50:  200nMAssay Description:Inhibition of endothelial lipase in hepatic lipase knock-out mouse plasmaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed