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Found 3 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM139989'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM139989(US8901140, 2 | US9358227, 2)
Affinity DataIC50:  3nMAssay Description:The following in vitro assay is to determine the activity of the tested compounds for inhibiting the proliferation of cancer cells, which has high ex...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM139989(US8901140, 2 | US9358227, 2)
Affinity DataIC50:  6nMAssay Description:The following assay may be used to determine the activity of the compounds of the invention for inhibiting EGFR kinase activity. The half maximal inh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM139989(US8901140, 2 | US9358227, 2)
Affinity DataIC50:  6nMAssay Description:The following assay may be used to determine the activity of the compounds of the invention for inhibiting EGFR kinase activity. The half maximal inh...More data for this Ligand-Target Pair
In DepthDetails US Patent