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Found 5 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM373723'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sabila Biosciences

Curated by ChEMBL
LigandPNGBDBM373723(US10246444, Example 90)
Affinity DataIC50:  2nMAssay Description:Inhibition of wild type EGFR (unknown origin) in presence of radiolabelled gammaATP by radioisotope filter binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sabila Biosciences

Curated by ChEMBL
LigandPNGBDBM373723(US10246444, Example 90)
Affinity DataIC50:  50nMAssay Description:KINOMEscan is based on a competition binding assay that quantitatively measures the ability of a compound to compete with an immobilized, active-site...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sabila Biosciences

Curated by ChEMBL
LigandPNGBDBM373723(US10246444, Example 90)
Affinity DataIC50:  387nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) in presence of radiolabelled gammaATP by radioisotope filter binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sabila Biosciences

Curated by ChEMBL
LigandPNGBDBM373723(US10246444, Example 90)
Affinity DataIC50:  550nMAssay Description:KINOMEscan is based on a competition binding assay that quantitatively measures the ability of a compound to compete with an immobilized, active-site...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sabila Biosciences

Curated by ChEMBL
LigandPNGBDBM373723(US10246444, Example 90)
Affinity DataIC50:  1.28E+3nMAssay Description:Inhibition of EGFR ex19del mutant (unknown origin) in presence of radiolabelled gammaATP by radioisotope filter binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed