Found 4 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50460714' TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology Co. Itd.
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology Co. Itd.
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R/T790M mutant cytoplasmic domain (668 to 1210 residues) expressed in baculovirus expression syst...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology Co. Itd.
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology Co. Itd.
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human GST-tagged wild-type EGFR cytoplasmic domain (668 to 1210 residues) expressed in baculovirus expression system using ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology Co. Itd.
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology Co. Itd.
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of EGFR L858R/T790M mutant phosphorylation in human NCI-H1975 cells after 1 hr by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology Co. Itd.
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology Co. Itd.
Curated by ChEMBL
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of wild-type EGFR phosphorylation in human A431 cells preincubated for 1 hr followed by EGF stimulation measured after 45 mins by ELISAMore data for this Ligand-Target Pair
