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Found 3 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50493387'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50493387(CHEMBL2425736)
Affinity DataIC50:  0.410nMAssay Description:Inhibition of wild type human EGFR tyrosine kinase assessed as Ulight-CAGAGAIETDKEYYTVKD phosphorylation after 15 mins by time-resolved fluorometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50493387(CHEMBL2425736)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells incubated for 1 hr followed by compound washout measured at 1 hr by Western blot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50493387(CHEMBL2425736)
Affinity DataIC50:  14nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells incubated for 1 hr followed by compound washout measured after 8 hrs by Western ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed