Found 1 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor [T790M,L858R]' and Ligand = 'BDBM50357312' TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Affinity DataIC50: 4.60nMAssay Description:In the case of Km ATP, EGFR T790M/L858R protein kinase activity was tested by Caliper mobility shift assay (referring to J Biomol Screen 14:31, 2009)...More data for this Ligand-Target Pair
3D Structure (crystal)