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Found 2 Enz. Inhib. hit(s) with Target = 'Estrogen receptor' and Ligand = 'BDBM269454'
TargetEstrogen receptor(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM269454((E)-3-(4-((6-hydroxy-2- (2-(2,2,2- trifluoroethyl)...)
Affinity DataIC50:  0.200nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM269454((E)-3-(4-((6-hydroxy-2- (2-(2,2,2- trifluoroethyl)...)
Affinity DataIC50:  12nMpH: 5.1 T: 2°CAssay Description:The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent