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Found
1
Enz. Inhib. hit(s) with Target = 'Estrogen receptor [307-554]' and Ligand = 'BDBM361518'
Target
Estrogen receptor [307-554]
(Homo sapiens (Human))
Astrazeneca
US Patent
Ligand
BDBM361518
(2,2-difluoro-3- ((1R,3R)-1-(5- fluoro-2-(2- ((3- f...)
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Affinity Data
IC50: 0.430nM
Assay Description:
ERα: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition...
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Target Info
PDB
UniProtKB/SwissProt
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Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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