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Found 5 Enz. Inhib. hit(s) with Target = 'Fatty-acid amide hydrolase 1' and Ligand = 'BDBM50296484'
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50296484((S)-{3-[(4-Chlorophenyl)-(2-chloropyridin-3-yl)met...)
Affinity DataIC50:  78nMAssay Description:Inhibition of human FAAH incubated 3 hrs prior to addition of arachidonylaminomethylcoumarin amideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50296484((S)-{3-[(4-Chlorophenyl)-(2-chloropyridin-3-yl)met...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human FAAH incubated 1 hr prior to addition of arachidonylaminomethylcoumarin amideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50296484((S)-{3-[(4-Chlorophenyl)-(2-chloropyridin-3-yl)met...)
Affinity DataIC50:  188nMAssay Description:Inhibition of human FAAH incubated 3 hrs prior to addition of arachidonylaminomethylcoumarin amideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50296484((S)-{3-[(4-Chlorophenyl)-(2-chloropyridin-3-yl)met...)
Affinity DataIC50:  291nMAssay Description:Inhibition of human FAAH incubated 1 hr prior to addition of arachidonylaminomethylcoumarin amideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50296484((S)-{3-[(4-Chlorophenyl)-(2-chloropyridin-3-yl)met...)
Affinity DataIC50:  973nMAssay Description:Inhibition of human FAAH expressed in CHO cells using 7-amino-4-methylcoumarine amide as substrate preincubated for 1 hr by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed