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Found 2 Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 4' and Ligand = 'BDBM333178'
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM333178(US10196436, Compound 28)
Affinity DataIC50:  55nMAssay Description:In each well of a 384-well plate, 0.5 ng/ul of wild type FGFR-4 (Carna Biosciences, Inc.) was incubated in a total of 12.5 ul of buffer (100 mM HEPES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM333178(US10196436, Compound 28)
Affinity DataIC50:  91nMAssay Description:Inhibition of N-terminal GST fusion tagged human FGFR4 cytoplasmic domain (460 to 802 end residues) expressed in baculovirus expression system preinc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed