Found 5 Enz. Inhib. hit(s) with Target = 'G-protein coupled bile acid receptor 1' and Ligand = 'BDBM50236238' TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute
Curated by ChEMBL
The Beckman Research Institute
Curated by ChEMBL
Affinity DataEC50: 680nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute
Curated by ChEMBL
The Beckman Research Institute
Curated by ChEMBL
Affinity DataEC50: 730nMAssay Description:Agonist activity at wild type TGR5 (unknown origin)More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute
Curated by ChEMBL
The Beckman Research Institute
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:Agonist activity at TGR5 expressed in NCI-H716 cells assessed as cAMP level after 60 mins by FRET analysisMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute
Curated by ChEMBL
The Beckman Research Institute
Curated by ChEMBL
Affinity DataEC50: 5.60E+3nMAssay Description:Agonist activity at TGR5 expressed in CHO cells by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute
Curated by ChEMBL
The Beckman Research Institute
Curated by ChEMBL
Affinity DataEC50: 580nMAssay Description:Agonist activity at human TGR5 expressed in CHO cells by luciferase assayMore data for this Ligand-Target Pair
