Found 3 Enz. Inhib. hit(s) with Target = 'G-protein coupled bile acid receptor 1' and Ligand = 'BDBM53721'
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute
Curated by ChEMBL
The Beckman Research Institute
Curated by ChEMBL
Affinity DataEC50: 2.39E+3nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute
Curated by ChEMBL
The Beckman Research Institute
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TGR5 in human NCI-H716 cells assessed as stimulation of intracellular cAMP accumulation incubated for 60 mins by HTR-FRET assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute
Curated by ChEMBL
The Beckman Research Institute
Curated by ChEMBL
Affinity DataEC50: 3.64E+4nMAssay Description:Agonist activity at human TGR5 expressed in CHO cells by luciferase assayMore data for this Ligand-Target Pair