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Found 5 Enz. Inhib. hit(s) with Target = 'Gag-Pol polyprotein [489-587]' and Ligand = 'BDBM50092152'
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50092152(2-Benzyl-5-(10-sec-butyl-9,12-dioxo-2-oxa-8,11-dia...)
Affinity DataKi:  0.600nMAssay Description:Inhibitory constant against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50092152(2-Benzyl-5-(10-sec-butyl-9,12-dioxo-2-oxa-8,11-dia...)
Affinity DataIC50:  56nMAssay Description:Inhibition of virion associated RT activity relative to untreated, infected control in cord blood mononuclear cells (CBMC) infected with HIV -1 TC354...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50092152(2-Benzyl-5-(10-sec-butyl-9,12-dioxo-2-oxa-8,11-dia...)
Affinity DataIC50:  60nMAssay Description:Inhibition of virion associated RT activity relative to untreated, infected control in MT2 cells of HIV-1 237288 strainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50092152(2-Benzyl-5-(10-sec-butyl-9,12-dioxo-2-oxa-8,11-dia...)
Affinity DataIC50:  100nMAssay Description:Inhibition of virion associated RT activity relative to untreated, infected control in MT2 cells infected with HIV-2 strain (ROD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50092152(2-Benzyl-5-(10-sec-butyl-9,12-dioxo-2-oxa-8,11-dia...)
Affinity DataIC50:  110nMAssay Description:Inhibition of virion associated RT activity relative to untreated, infected control in PBMC cells infected with HIV-1 237288 strainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed