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Found 3 Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM50458173'
TargetGenome polyprotein(Hepatitis C virus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50458173(CHEMBL4217239)
Affinity DataKi:  30nMAssay Description:Inhibition of HCV genotype-1a full length NS3 protease R155K mutant preincubated for 10 mins followed by Ac-DED(Edans)EEAbuj-[COO]ASK(Dabcyl)-NH2 add...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50458173(CHEMBL4217239)
Affinity DataKi:  135nMAssay Description:Inhibition of HCV genotype-3a full length NS3 protease preincubated for 10 mins followed by Ac-DED(Edans)EEAbuj-[COO]ASK(Dabcyl)-NH2 addition in pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50458173(CHEMBL4217239)
Affinity DataKi:  160nMAssay Description:Inhibition of HCV genotype-1a full length NS3 protease preincubated for 10 mins followed by Ac-DED(Edans)EEAbuj-[COO]ASK(Dabcyl)-NH2 addition in pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed