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Found 1 Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM9682'
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9682(2-methylpropyl N-[(1S)-2-[(2S,4R)-4-(tert-butylsul...)
Affinity DataKi:  120nM ΔG°:  -40.2kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed