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Found 1 Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM9933'
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9933((2S)-2-(2-{3-[(2S)-2-[(3S,4S)-4-cyclohexyl-3-hydro...)
Affinity DataKi:  4.20E+4nM ΔG°:  -25.4kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed