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Found 1 Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM9935'
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9935((2S)-2-{2-[3-({[(3S)-3-cyclohexyl-3-{[(2-methylpro...)
Affinity DataKi:  2.10E+3nM ΔG°:  -33.0kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed