Found 2 Enz. Inhib. hit(s) with Target = 'Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50327981' TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of human geranylgeranyltransferase-1 assessed as incorporation of [3H]GGPP into H-Ras-CVLLMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Mus musculus)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Rap1A geranylgeranylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
