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Found 3 Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50368971'
TargetGlucocorticoid receptor(Homo sapiens (Human))
Oric Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50368971(CHEMBL4159987)
Affinity DataIC50:  5.60nMAssay Description:Antagonist activity at human GR expressed in CHO-K1 cells assessed as reduction in dexamethasone-induced response incubated for 20 hrs by luciferase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Oric Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50368971(CHEMBL4159987)
Affinity DataIC50:  5.60nMAssay Description:Antagonist activity at human glucocorticoid receptor expressed in CHO-K1 cells harboring firefly luciferase gene after 20 hrs by One-Glo luciferase r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Oric Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50368971(CHEMBL4159987)
Affinity DataEC50: >2.50E+3nMAssay Description:Agonist activity at human GR expressed in CHO-K1 cells incubated for 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed