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Found 2 Enz. Inhib. hit(s) with Target = 'Glutamate dehydrogenase 2, mitochondrial' and Ligand = 'BDBM109086'
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM109086(US10793535, Cmpd ID 727 | US8604016, 670 | US99382...)
Affinity DataIC50:  5nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM109086(US10793535, Cmpd ID 727 | US8604016, 670 | US99382...)
Affinity DataIC50:  23nMAssay Description:Glutaminase reaction buffer was prepared [50 mM Tris-HCl pH 8.8, 150 mM K2HPO4, 0.25 mM EDTA, 0.1 mg/ml BSA (Calbiochem no. 2960), 1 mM DTT, 2 mM NAD...More data for this Ligand-Target Pair
In DepthDetails US Patent